In this last years infant-psychoanalysis has much developed and an integration with Attachment Theory’s researches and techniques happened: so many and different Psychotherapy Schools developed. These psychotherapies are focused on the mother (or caregiver) rather than on the child, chiefly if he is not a baby. Principal vehicle of the communication which incomes between the therapists and his “patients” is not verbal, like adult psychoanalysis. Such a development allowed to discover that therapeutic effect – that is what make mental structures change – also in adult depends on affective messages, vehicled by that non verbal communication which constitutes that specific interpersonal relation. Such a discovery focused the importance and complexity of the interpersonal Relation, as the most structurant situation. Structuring effect, non only psychic but also neural, is the foundation of children brain. Cerebral maturation concept is nowadays changed: it depends from primary relational learning. Structuring effect may be negative too: here is psychopathology, which in little children is silent. Relationship with its continuous non verbal communication is not conscious. Affective messages circulation is automatic and unconscious. A competent therapist must be formed in achieving, but in part, a capacity in being conscious about it.